Structural basis of supercoiling-induced CRISPR–Cas9 off-target activity - Nature

Nature, Published online: 25 March 2026; doi:10.1038/s41586-026-10255-7Cas9 structures explain topology sensing and off-target activation.

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Structural basis of supercoiling-induced CRISPR–Cas9 off-target activity - Nature

Source: Nature

Nature, Published online: 25 March 2026; doi:10.1038/s41586-026-10255-7Cas9 structures explain topology sensing and off-target activation.

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